منابع مشابه
Current research in perineural invasion of cholangiocarcinoma
BACKGROUND Perineural invasion is a common path for cholangiocarcinoma (CCA) metastasis, and it is highly correlated with postoperative recurrence and poor prognosis. It is often an early event in a disease that is commonly diagnosed in advanced stages, and thus it could offer a timely therapeutic and diagnostic target if better understood. This article systematically reviews the progress of CC...
متن کاملPrognosis and Progression of ESCC Patients with Perineural Invasion
Perineural invasion (PNI) has been recognized as a poor prognostic factor in several malignancies, but the definition and pathogenesis of PNI in esophageal squamous cell carcinoma (ESCC) remains to be defined. PNI was evaluated by H&E staining and S100 immunohistochemistry. The predictive value of PNI in the prognosis of ESCC patients was analyzed. PNI was evaluated in vitro and in vivo. A tota...
متن کامل[Management of basal cell carcinoma with perineural invasion].
The presence of perineural invasion in skin tumors constitutes a major risk factor for local recurrence.1-3 Perineural invasion is not a common finding in basal cell carcinomas, with an estimated incidence that, depending on the series, varies between 0.17%2 and 3.8%.4 The frequency is higher in more aggressive histological subtypes and in recurrent tumors.1,2,4,5 The patient was a 69-year-old ...
متن کاملInteraction of the Sympathetic Nerve with Pancreatic Cancer Cells Promotes Perineural Invasion through the Activation of STAT3 Signaling Running title: Role of Sympathetic Nerve in Perineural Invasion
Kun Guo, Qingyong Ma, Junhui Li, Zheng Wang, Tao Shan, Wei Li, Qinhong Xu, Keping Xie Department of Hepatobiliary Surgery, First Affiliated Hospital of Xi'an Jiaotong University, Xi’an, Shaanxi, People’s Republic of China; Department of General Surgery, Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an, Shaanxi, People’s Republic of China; Department of Gastrointestinal Medical Onc...
متن کاملThe chemokine (CCL2-CCR2) signaling axis mediates perineural invasion.
UNLABELLED Perineural invasion is a form of cancer progression where cancer cells invade along nerves. This behavior is associated with poor clinical outcomes; therefore, it is critical to identify novel ligand-receptor interactions between nerves and cancer cells that support the process of perineural invasion. A proteomic profiler chemokine array was used to screen for nerve-derived factors s...
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ژورنال
عنوان ژورنال: Indian Dermatology Online Journal
سال: 2015
ISSN: 2229-5178
DOI: 10.4103/2229-5178.153018